Rocksmith+ was working perfectly fine until it performed a software update yesterday (July 14). I had played it for several days prior to that trying out all the new features. However, since that update, the sound from my guitar when I play a note is just loud static, pops, and crackles. I tried it in RS2014, and my guitar sounds perfectly fine. I have tried RS+ with audio exclusivity on and off but still just get garbled noise when I play a note. I have uninstalled and reinstalled RS+, but that did not fix the problem. Each time I go back to RS2014, the notes sound clear, so this has to be an issue with RS+ and not hardware drivers or anything like that. I would love to continue evaluating RS+, but it is completely unplayable at this time.
Update - I started messing with all the graphics settings in the game and noticed that the sound started improving as I turned down the graphics. The crackles and pops decreased a bit as I turned down the graphic settings. So I turned all the graphics settings down to their lowest level (or in some cases turned the option off), and now I can hear the note from my guitar. There is still a lot of crackles and pops when I play a note, but I can hear the note. However, the notes sound like a MIDI synthesizer, and not really a guitar tone.
Before you say it's my computer, I'm running an Acer Nitro 5 with an i5 @ 2.4 GHz, 8 GB RAM, Nvidia GeForce with 4 GB RAM. This should be more than enough to run the game on the highest settings. And it did. The game ran perfectly until the update last week.
Is anyone from Ubisoft or the game development team reading these posts? It would be nice to get some feedback that they are at least looking into these issues.