In game, I've just completed Nick Rye's recruitment mission and the game crashes during a speech by John.
It's a new game+ run and I've liberated Jacob and Faith's regions and am almost up to the final mission of John's region. I've had no issues up to this point, but now the game just crashes during that speech every time I restart.
UPDATE - game seems to run fine now after I verified files and it reinstalled directx and .net stuff.