it is even suspected now they may have sabotaged the SHD network by restricting certain SHD functions and information thus the Division is designed to Fail their mission from the very beginning which is why everything happened with the First Wave in Manhattan and why the JTF suddenly pulled back.
The Division, by design, was never meant to succeed and the people chosen are picked specifically because they are not only skilled but have serious mental issues that will make them go Rogue easily and thus turn the Division into a "Rogue Agency" so the Black Tusks can look like "Saviors". However, they never expected some of those crazy people chosen to be crazy enough to save the Cities and stay true to a path that does not lead toward tyranny and loss of freedom for the people they are trying to protect.
As for ANNA, it seem ANNA is made to be ISAC without those restrictions placed on by the Black Tusk's Client. I suspect ANNA may replace ISAC later since we may need ANNA to defeat the Black Tusk's Client and expose them to the world along with what they have done.