I play a lot of coop with friends (Currently the only mode I enjoy the game) and there is a crucial change between wildlands and breakpint.
If you disable the enemy markers you also can not select enemies with "Q". In Wildlands that was possible. The enemy markers were not there but the markers for Target A, B, C and D where available. You could select up to the amount of players you were with. This was nice because it allowed easier coordination. It would be cool If you could separate the two options again. Also, the kill drone is not usable when the markers are disabled. But that's another story.