First off was running the Air and Space Museum mission on Challenging via matchmaking. We clear the waves out only to have the icon tell us one last guy was beyond the door down the ramp that leads inside. After a few skill and grenade attempts to reach him, I left group and went to do some control points. I cleared a Territory, grabbed the key and was unable to open the chest. Mission icon highlighted it but no 'F' prompt appeared. Gave up and headed to a Propaganda. On the way (using survivor perk to gain ammo) my cover-to-cover action simply stopped working. I could go into cover, move in and out, and dodge roll but couldn't trigger motion.
Then this happened.
Just couldn't walk into that section of the city.
Haven't had any of these happen before today (with the nonspawning enemy on a rare exception).