Look like your not alone..
https://www.reddit.com/r/thedivision/comments/b14wml/why_are_my_skills_turni
ng_off_and_triggering_a_15/
Me too....my missions reset themselves. Some of the them disappears off of the gane. My supply drop...Gone! What supply drop. The NPCs disappear. It's horrible! i expected so much more from a game that har two individual beta testings! im thoroughly disappointed