If by skill means they avoid more your attacks and use more special moves (like red moves) and retreat towards their friends instead of chasing you alone, and ducking / taking cover faster and more often if you shoot with the bow, then yes they do all those.
Also they have more HP / armor, and you need poison or fire damage to chew through that HP at acceptable rate. Otherwise you can dump on hard up to 3x Rank 2 OP combos into a simple grunt and he's still alive and will drink a potion (similar to your heal).