Solo/single player and Offline... Yes
Solo/single Player w/o Blob AI squad... No
If you don't want the Squad Blob interfering or going loud w/o your expressed orders you must keep them on hold at all times. if you move ahead of them, check your map, see where they now are and put them on hold again... rinse and repeat. This was the case for the CB & OB but I doubt very much it changed for Final Release game.