Hello Feiwei,
had the same Problem. I did the following:
1. Deactivated my virus scanner (under services.msc)
2. Changed the name of the folder the game was in
3. Deinstalled the game
4. Moved the game to the disk where Uplay is installed on
5. Changed name back to its original
6. Installed it over Uplay
7. Waited till it verified that all data is already present and started the game.
Sincerely,
Michael